Well Brain
  • Dr. Jacobs
  • Pediatric Services
  • Teletherapy
  • Community Involvement
  • Blog
  • FAQ
  • Contact
    • Schedule a Session

What about medication?

8/31/2015

0 Comments

 
A topic that comes up frequently with families is whether or not medication is an appropriate part of treatment.  This is a personal decision and it is important to take into account many factors. The additional complication of the stigma of mental illness, can make this decision even harder. The good news is that there is good research on what the combination of medication (such as a selective serotonin reuptake inhibitor; SSRI) and cognitive behavior therapy (CBT) can offer. 

During graduate school, I worked on the largest clinical trial for adolescent depression to date: the Treatment for Adolescents with Depression Study (TADS).  Northwestern was one of 13 sites in this clinical trial.  439 adolescents were randomized to receive fluoxetine (Prozac), CBT, the combination of CBT+fluoxetine, or a pill placebo.  What we found is that the combo treatment was more efficient in reducing symptoms of depression and suicidality over the short-term (12-weeks).  CBT alone caught up to medication and combo at 36 weeks, but it is important to remember that 36 weeks is a long time in the life of a teenager!  

If there is functional impairment (meaning the symptoms are getting in the way of the teen's life, such as in school or socially) then it may be important to speed up time to improvement.

Interesting research with animals suggests that extra serotonin may help us learn better. CBT takes a lot of work and some of our mental habits may be very strong. My clinical observation is that medication can help loosen up some of the negative thinking, so that it is a little bit easier to try having the thought "I can do my best to approach this problem" as opposed to the old habit of "I can't do anything right."

Medication isn't necessarily right for everyone and particularly in mild cases it may not be necessary.  On the other hand, it can be a very useful tool on the road to wellness.

Mark Reinecke, PhD was my graduate school advisor and the Principal Investigator at the Northwestern cite.  You can read more about him here. TADS was funded by the National Institutes of Mental Health (NIMH). NIMH has resources regarding adolescent depression here.

Here are a few of the TADS papers if you are interested in doing some background reading:


tads_12_week.pdf
File Size: 171 kb
File Type: pdf
Download File

tads_36.pdf
File Size: 168 kb
File Type: pdf
Download File

0 Comments

Your comment will be posted after it is approved.


Leave a Reply.

    Picture

    Dr. Rachel H. Jacobs

    I am a clinical psychologist who specializes in training resiliency and wellness among young adults.

    View my profile on LinkedIn
    My Profile on Psychology Today

    Categories

    All
    Adolescence
    Anxiety
    Depression
    Medication/Combo Treatment
    Mindfulness
    Parenting
    Research
    Rumination
    TADS
    Telehealth
    Treatment

    RSS Feed

Meet DR. JACOBS

Dr. Rachel Jacobs, PhD
Ph.D. in Clinical Psychology
Northwestern University Feinberg School of Medicine

Postdoctoral Fellowship
Columbia University
New York State Psychiatric Institute
​
I combine cognitive behavioral therapy (CBT) with strategies from mindfulness to provide a comprehensive wellness approach to help young adults and college students overcome depression and anxiety and live healthier, more fulfilling lives.
Northwestern Medicine Feinberg School of Medicine
Stay in touch!
  • Dr. Jacobs
  • Pediatric Services
  • Teletherapy
  • Community Involvement
  • Blog
  • FAQ
  • Contact
    • Schedule a Session